Endocrine Abstracts

Subclinical hypothyroidism is defined as a biochemical abnormality characterized by an elevated serum level of sTSH with normal thyroid hormones (FT4) and no clinical symptoms. The objective of this study was to asses whether patients with subclinical hypothyroidism have a risk of hypercholesterolemia. We have evaluated 37 adults (34 female and 3 male), mean age 49.20±9.65 years, with laboratory confirmed subclinical hypothyroidism, sTSH value above of 4.5 mU/L and normal...

Adrenal incidentalomas are referred as clinically silent adrenal masses discovered incidentally during diagnostic testing or treatment for conditions not related to suspicion of adrenal disease. Certain percent of them are hormonally active and autonomous cortisol secretion is reported with increasing frequency. The aim of the study was to assess value of 1mg-DST in subclinical Cushing’s syndrome (CS) compared to the other forms of adrenal incidentalomas. We have evaluate...

Background: It was shown that women with polycystic ovary syndrome (PCOS) are at an increased risk of COVID-19. However, it is not known whether COVID-19 has any effects on reproductive health of PCOS patients.Objectives: Aim of the study was to evaluate possible effects of COVID-19 on reproductive health in patients with PCOS.Methods: An anonymous survey about reproductive health was conducted in PCOS patients and healthy control ...

Background: Reproductive health is an integral part of a women’s general health and is influenced by various endogenous and exogenous factors.Objectives: The aim was to detect the possible effects of COVID-19 on women’s reproductive health.Methods: We created an anonymous survey about reproductive health and shared it with women of reproductive age. Regarding menstrual cycle characteristics all women used the smartphone a...

Introduction: Adrenal neurilemoma (or schwannoma) are vary rare tumors. They usually present as incidental finding in asymptomatic patients, which makes them dificult to diagnose preoperatively.Case report: We present a 60 year old woman with incidentally discovered adrenal mass of 5 cm on the right side. The tumor was detected by ultrasound and then it was confirmed by MSCT scan. We performed careful endocrine workup. Results showed normal levels of uri...

Introduction: Insulin resistance is quite common among obese individuals. Lifestyle interventions like diet interventions and regular physical activity are still important and safe first-line therapy.The aim of this study was to assess the effects of diet and physical activity-induced weight loss on insulin resistance in extremely obese patients.Methods: Forty-four patients (mean age 41.05±10.23 years) were consecutively recru...

Adrenal incidentalomas are incidentally discovered adrenal tumors by imaging methods without any prior suspicions of adrenal disease. Most of these tumors are functionally inactive but thorough investigations can reveal discrete hormone excess. Chromogranin A(CgA) is expressed in neuroendocrine cells throughout the body, including large and small intestine, adrenal medulla and pancreatic islets. It is a marker for carcinoid tumors, paragangliomas, and other neuroendocrine tumo...

Premature ovarian failure (POF) is characterized by amenorrhea, hypergonadotropism and hypoestrogensm in women under 40 years. Sex steroids play an important role in maintaining bone mass and cessation of ovarian function results in significant bone loss.Objective: To evaluate bone mass density (BMD) and factors influencing it in women with POF.Design & methods: First group of 144 women with spontaneous POF (I), 39.7±7.6 y...

Background: Recent studies showed that cortisol autonomy is age and sex dependent and highly associated with higher all-cause mortality in patients with adrenal incidentalomas (AI). Dehydroepiandrosterone sulphate (DHEAS) has been recognized as a valuable diagnostic tool in patients with (possible) autonomous cortisol secretion.Objectives: As DHEAS levels are sex and age specific we aimed to evaluate its value as a diagnostic tool in patients with adrena...

Background: Menstrual cycle characteristics are essential indicators of a woman’s reproductive health. The reliability of auto-reported data assesment of menstrual cycle length has been questioned. Objectives: The aim was to evaluate the reliability of auto-reported data on menstrual cycle regularity. Methods: We created an anonymous survey about reproductive health and menstrual cycle characteristics and shared it with women ...